Category: iewfhvzf

Getting murkier…

first_img…in sugar divestmentYour Eyewitness was thrown for a loop when he learnt DDL pulled out of the bidding for Enmore Estate at the last moment. When DDL discovered the production from the three “grinding” estates couldn’t supply them with enough molasses to produce their world-class rums, they worked with the SPU to restart the Emmore operations to supply the rest, didn’t they? What did they learn?Now, no matter how you slice it or dice it, DDL’s a very well-run outfit, and it behooves the SPU – if no one else — to examine clearly why DDL chose to remain on the side-lines and not the “middle walk”! They said they couldn’t “find a model that would fit with (their) current investment and development strategy”. What this means, in your Eyewitness’s estimation, is the SPU and Price Waterhouse structured a deal that just doesn’t make financial sense.Most likely, they demanded too much money for factories (LBI was included?) that were cannibalised and fields that have been allowed to revert to bush. DDL said they’ll wait to see if anyone else will buy Enmore on the present terms, and then buy molasses from them. Why buy the whole cow when you can buy milk as you need it? Let others pick up the big tab; spend millions (US!) to fix up the factory, and then struggle to attract a labour force for the fields!! And if perchance they produce any sugar, they’ll produce the molasses as a by- product, which DDL can snap up.DDL went on to say if there were no takers, then they’ll make another bid. Meaning, of course, they expect the SPU/Price Waterhouse will revise the “model” – read “asking price”.But your Eyewitness isn’t so sanguine about some other bids – especially that one by the Trini company which has specialised for the last 50 years on importing car parts and fixing engines. Your Eyewitness could swear the SPU said they give the greatest weight to the demonstrated ability of bidders that could show how they’ll run the entity. And they were impressed by these fellas: who never ran a sugar operation in their lives, and never showed interest in the Caroni sugar operations that were shuttered nearly two decades ago?Something ain’t kosher. Especially when the outfit had, a year ago, already submitted a bid to Go-Invest which just didn’t make sense. And talking about “kosher”, is that other bidder Kadem the Jewish condiment maker, who started out bottling grape juice?And no takers for Wales?…in LGE electionsEveryone and their (political) uncles conceded that the turnout in the LGE by the Disciplined Forces was “poor”. Meaning “miserable”! Now, if you have forces that have been explicitly called “disciplined” and who’re supposed to be patriotic and trained to obey orders, but yet don’t show up to exercise their franchise, something’s radically wrong with our country!!Now all it would’ve taken to ensure a high turnout was for the officers in the GDF, GPF, Fire Service and Peoples Militia to give a direct order to their charges!! So the officers didn’t give the orders? If they didn’t, then something is wrong with the officer corps and their understanding of their role in a democracy – especially when most of them will end up running the Government!! And if the order was given but the troops didn’t obey, we have an even bigger problem!! Is this “poor turnout” going to be repeated if the Vennies pour across our western border? What’s going on here?We expect President Nagamootoo to launch a CoI to find out!!…on the successionWhile we all expect the President to return all chipper and all that, we’ve got to plan for the worse. So will Nagamootoo be allowed to be President till 2020?God forbid!!last_img read more

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GOP may need to find new home in Whittier

first_img AD Quality Auto 360p 720p 1080p Top articles1/5READ MORE11 theater productions to see in Southern California this week, Dec. 27-Jan. 2165Let’s talk business.Catch up on the business news closest to you with our daily newsletter. Something went wrong. Please try again.subscribeCongratulations! You’re all set! WHITTIER – The Republican Party recently leased the bottom floor of the former Ibiza Restaurant, but there’s just one problem — legally, they aren’t allowed to be there. City codes only allow retail and restaurants for Uptown Whittier. Now the City Council will review on Tuesday a GOP request for an exception. Two years ago, however, the city refused to make a similar exception when Democrat Party officials sought to lease a building on Greenleaf Avenue.last_img read more

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Sunderland flop and ex-Chelsea man Papy Djilobodji completes loan move

first_imgSunderland have announced that defender Papy Djilobodji has joined Dijon on a season-long loan.The 28-year-old Senegal international will make the switch to the Ligue 1 club for the rest of the campaign.“Sunderland AFC have confirmed that Papy Djilobodji has joined Dijon FCO on a season-long loan,” the Championship club said in a statement on their official website.Earlier, Black Cats goalkeeper Max Stryjek joined League Two’s Accrington on a season-long loan. Papy Djilobodji has moved to Dijon on loan 1last_img read more

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The staggering amount of money Liverpool will lose after Coutinho’s move to Bayern

first_imgBarcelona have been desperate to shift the 27-year-old forward for much of the summer following a disappointing season – and Tottenham were among the clubs linked with his signature. Philippe Coutinho has completed a season-long loan move to Bayern Munich According to Spanish publication Sport, the Reds were due an additional £18m once Coutinho played 100 games for Barcelona, with a further £5m if the Catalan club won the Champions League with the Brazilian in the side. Philippe Coutinho’s move to Bayern Munich could well end up costing Liverpool a huge sum of money.Bayern completed the singing of Coutinho on a season-long loan from Barcelona with an option to buy the Brazilian for £109.8million next summer.The Brazil international looks set to end his sorry spell at the Nou Camp after the German champions agreed to pay £7.78m to take him on loan before making the move permanent at the end of the season. AFP or licensors But after rejecting a move to north London, the Spanish and German champions have confirmed the agreement for Coutinho to spend this season in Munich.And it may mean that his former side miss out on a huge pay day.Liverpool received £105m in up front payments from Barca when the deal was completed in January 2018, with an additional £37m set to be paid in instalments. But by joined the German champions on loan for the season, Coutinho has ended Liverpool’s chances of receiving this money, at least for the time being.As mentioned previously, Bayern have not only agreed to pay a loan fee for Coutinho’s services for the season, but will also pay the majority of his extortionate wages for the campaign. The Brazil international had struggled to settle at Barca center_img 2 2 Trophies: Three (two league titles, one Copa del Rey)Games: 75Goals: 21Assists: 11 He may not have been able to nail down a regular spot in a very good Barcelona side, but he still leaves with impressive stats AFP or licensors Coutinho at Barcalast_img read more

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Rodgers: Celtic players were first class in qualifying

first_imgBrendan Rodgers said he was delighted with his side’s qualifying campaign after seeing them complete an 8-4 aggregate win over Astana to reach the Champions League group stage.Celtic lost 4-3 on the night but achieved their early season goal with plenty to spare and now go into Thursday’s draw with the biggest names in football.Rodgers reflected on the defeat but said that the bigger picture was far more pleasing as he had dealt with injury to take his side through four stages of qualification.“I assess overall,” he said. “Over the course of two games against Astana we scored eight goals . “I thought we were going to get through this campaign without the anxiety but that little period (at the start of the second half) they scored two quick goals. We were working on the side to plug gaps. “I then have to give credit to the players because they were on the ropes for 15-20 minutes, but they regained their composure.” “Yeah, we were disappointing tonight but across the campaign I’ve had to play midfield players at centre-half, right-backs at centre-half, put kids in, play games without strikers so all in all the players have been absolutely first class, deserved to qualify and we’ll look forward now to the draw.”Despite that, the Celtic boss admitted he was a little unhappy with the performance in the second leg defeat but said his players showed character to bounce back after an Astana onslaught in the second half.“It’s mixed emotions because we didn’t defend well enough and our possession at times wasn’t good enough either,” he said.“I said to the players (at half-time) we started the game very well. We wanted to control the tempo but we were too loose in our passing and our positioning, we weren’t compact enough when they had the ball. That didn’t allow us to press. last_img read more

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Prosecutor Says Officer Was Justified in Shooting

first_imgClark County’s Prosecutor says a Clarksville Police Officer was justified in shooting on Friday, April 26 that killed a Clarksville man.Max David Helton, 43, of 514 Howard Street in Clarksville was shot last Friday evening. An autopsy conducted by the Jefferson County, Kentucky Coroner’s Office listed the cause of death as a gunshot wound to the chest.  Clark County Prosecutor Jeremy Mull reviewed the investigation conducted by detectives from the Indiana State Police in Sellersburg and advised the officer was justified in using deadly force against Max Helton and that no charges would be filed. The officer was been identified as Patrolman Tyler Ash of the Clarksville Police Department.  Patrolman Ash is a two year veteran of the department. The review concluded that Officer Ash properly used deadly force after Helton pointed a firearm at the officer and after being instructed multiple times to drop the weapon.At approximately 10:30p last Friday evening, Officers from the Clarksville Police Department were dispatched to the residence located at 514 West Howard Street after receiving a 911 call for a domestic disturbance, possibly involving a gun.  State Troopers from the Sellersburg Post also responded to assist.As a result of the preliminary investigation, ISP detectives believed that officers from the Clarksville Police Department and Indiana State Police arrived on-scene shortly after receiving the 911 call.  During the investigation, officers witnessed a male subject with a gun at the doorway, the man then retreated into the house and barricaded himself and the original caller inside the residence. As the investigation continued, officers once again encountered the subject who was still brandishing a handgun. The subject refused commands to drop the weapon, and at least one officer from the Clarksville Police Department fired upon the subject and struck him. Officers then rendered first-aid to the subject who was transported to the University of Louisville Hospital where he later died from his injuries. Chief Mark Palmer of the Clarksville Police Department requested the assistance of ISP detectives and crime scene technicians to investigate the shooting.  Units from the Indiana State Police were assisted by the Clarksville Police Department and the Jefferson County, Kentucky Coroner’s Office.last_img read more

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South Africa’s Dakar triumph

first_imgAlfie CoxFor Alfie Cox, a veteran of the Dakar as a motorcyclist on a factory-supported KTM, contesting the 2009 race in Argentina and Chile as a privateer was a very tough challenge. Spaniard Marc Coma took victory in the motorbike class, dominating to win by almost an-hour-and-a-half over second placed Cyril Despres. The 2009 edition proved to be a highly successful one for South Africans. Navigator Ralph Pitchford was second across the line with De Villiers’ Volkswagen Touareg teammate, Mark Miller of the United States, just eight minutes and 50 seconds behind the winners. Dakar Rally in South America!The Dakar Rally name was certainly misleading this year. Due to safety fears, last year’s event had been called off at the last minute; this time around the organisers took no chances and elected to stage the race in Argentina and Chile. Firdaus Kabirov, driving a Kamaz, won the trucks title, while Czech rider Josef Machacek, on a Yamaha, won the quads category. “I am really happy for the team, for Volkswagen, who have backed us for five years to achieve this win.” “Jurgen wanted to finish a Dakar and earn a Finisher’s Badge in the year that he turned 50, while I wanted to race through another major desert. That we achieved, but it was not easy. De Villiers had previously come agonisingly close to victory in the Dakar in 2006, when he finished second, and he was leading in 2007 when his engine caught fire and scuppered his chances of victory. Further down the field, Alfie Cox, so often a leading contender in the motorbike category, achieved his goal of simply finishing the 9 574-kilometre race in his Porsche-powered buggy. With De Villiers finishing first, Mark Miller second and Dieter Depping sixth, all ahead of the first Mitsubishi finisher, Volkswagen well and truly ended the Japanese manufacturer’s extraordinary run of seven successive Dakar Rally victories. ‘It’s absolutely incredible’“It’s absolutely incredible,” De Villiers said afterwards, “I have never felt such emotion. “I couldn’t stop counting up how many kilometres remained. I have to say, it’s an incredible feeling. center_img “This year the race was very, very tough in general,” Cox said. “The top drivers like Peterhansel, Sainz, Al Attiyah and many others withdrew from the race. Those who continued suffered in their state-of-the-art machines; it was just so much worse for the privateers and amateur teams. Having seen some of the towering dunes in the desert during this year’s race, television viewers could have been forgiven for thinking the event was still taking place in Africa. ‘A massive achievement’“Only 55% of all the competitors who started this year’s race managed to get to the start of today’s (final) stage,” Cox noted. “Finishing the Dakar is a massive achievement.” In addition, two Nissan Navara pick-ups, especially built by Nissan Motorsport in South Africa for the Dakar Rally, finished in fourth and fifth places. 19 January 2009 After making it to the finish with his co-driver, Jurgen Schroder from Germany, he reflected back on the race: “We are exhausted, but very proud that we persevered and very satisfied with what we achieved,” he said. Third place went to David Fretigne, who was one of only two riders in the top 10 who was not on a KTM. Giniel de Villiers, together with German navigator Dirk von Zitzewitz, claimed victory in the Dakar Rally at the weekend when he safely negotiated the final 227-kilometre stage to become the first South African winner of the world-famous event. Would you like to use this article in your publication or on your website? See: Using SAinfo materiallast_img read more

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SA urges Canada to stay in Protocol

first_img2 December 2011 As delegates from 190 countries seek to negotiate a new international agreement for cutting carbon emissions at COP 17 in Durban, South Africa has urged Canada to reconsider entering into a second commitment period for the Kyoto Protocol. “South Africa believes the climate change talks must be inclusive to assist the process of ensuring a balanced outcome to emerge from the current talks,” Environmental Affairs Minister and leader of the South African delegation at COP 17, Edna Molewa, said in Durban on Thursday. Molewa said the effects of climate change were real and “already here with us”. The 17th Conference of the Parties (COP 17) to the UN Framework Convention on Climate Change (UNFCCC), currently taking place in Durban, is also the 7th meeting of parties to the Kyoto Protocol, which is due to expire at the end of 2012, unless renewed.Canada ‘made similar threats last year’ Reports say Canada, which has failed to meet its emissions reduction targets under the Kyoto Protocol, will announce next month that it will formally withdraw from the treaty. UNFCCC executive secretary Christiana Figueres confirmed this week that Canada had made similar threats to pull out of the Protocol last year. South Africa called on Canada and other developed countries to ensure that they heeded the call made by the developing countries, particularly in Africa and the Small Island Developing States, who bear the brunt of climate change.Kyoto Protocol ‘an important first step’ “The Kyoto Protocol is an important first step towards a truly multilateral rules-based legally binding global emission reduction regime that will stabilise GHG emissions, and provides the essential base for international agreement on climate change involving the participation of all countries in accordance with their common but differentiated responsibilities and capabilities,” Molewa said. The first commitment period of the 1997 treaty is coming to an end next year, and developing countries are pushing for a second commitment period, but major economies, including the United States and Japan, are refusing to commit. Analysts say the reluctance by Canada to sign up for a second commitment may further strengthen the position by some developed countries that the Kyoto Protocol was “flawed”. The European Union has said it would agree to the new commitment to the Protocol but has placed conditions on this, including the demand for a change in the framework of the convention. Source: BuaNewslast_img read more

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Sreesanth, Two Other Rajasthan Players Arrested for Spot-fixing

first_imgThe Special Cell of the Delhi Police arrested Sreesanth and the other two cricketers last night from Mumbai for their alleged role in spot-fixing and Related Itemslast_img

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Gene-editing method revives hopes for transplanting pig organs into people

first_imgThanks to a powerful new gene-editing technique, researchers have made a stride toward engineering safer pig organs for human transplants. In a paper in Science today, they describe using the CRISPR editing method in pig cells to destroy potentially harmful DNA sequences at 62 sites in the animal’s genome. It’s the most extreme example to date of the precise yet widespread genetic changes possible through CRISPR. It’s also raising hopes that the technology can finally render pig organs fit for human bodies—a goal that some of the paper’s authors are already pushing further with a private company.About 122,500 people in the United States alone are waiting for a life-saving organ transplant, and some have argued that a steady supply of pig organs could make up the shortage, because they are similar in size to those of people. But so far, no one has been able to get around the violent immune response that pig cells provoke. And these cells pose another, longer term potential risk: Their DNA is riddled with many copies of a DNA sequence that is the remnant of a virus and can still produce infectious viral particles. This porcine endogenous retrovirus (PERV) has been shown to move from pig to human cells in a dish, and to infect human cells transplanted into mice with weak immune systems.These shadowy PERV sequences are the target of the new CRISPR experiment, from geneticist George Church of Harvard University and colleagues. Church believes the new work could revive the idea of xenotransplantation, as the use of animal organs in people is called. “Basically, this whole field has been in the doldrums for 15 years,” he says. “There’s been kind of a few true believers that had it on life support. But I think this changes the game completely.”Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)With CRISPR, a method based on the ancient defense mechanism that bacteria use to demolish the DNA of invading viruses, researchers can target a specific point in a genome with a short strand of guide RNA and then slice it with an enzyme to precisely disrupt a gene or insert a new one. Church’s team designed guide RNA that targets a gene common to all 62 of the PERV sequences in the DNA of pig kidney cells. In a small subset of these cells, the CRISPR system obliterated every instance of the targeted gene—by far greatest the number of gene changes so far achieved with a single round of CRISPR. And those edited cells showed up to a 1000-fold reduction  in their ability to infect human kidney cells with PERV in a lab dish.That cells even survived having their DNA hacked up in 62 places is remarkable, says molecular biologist Jennifer Doudna of the University of California, Berkeley, one of the original developers of CRISPR. The same approach could be useful as a research tool to probe the function of many repetitive sequences nestled in the human genome, some of which appear to be activated during viral infections, she says. “Maybe this will encourage labs to say ‘Hey, let’s make a bolder change in one shot.’” Other groups have managed to modify up to six sites, and up to five different genes, at a time.Church cautions that editing many instances of a single, repetitive gene sequence isn’t the same as targeting many unique genes at once—which will be necessary if CRISPR is to become a treatment for complex genetic diseases, for example. He suspects the experiment worked because it took advantage of an apparently rare phenomenon called gene conversion in which DNA sites already inactivated by CRISPR helped stop other recently cut sites from being correctly repaired by the cell, leading to a snowball effect that resulted in all the PERV copies ending up deactivated for good. “We’re not convinced that what we did is generalizable,” he says. “It doesn’t mean that we can now change 62 different genes easily.”But the result has immediate relevance for developing transplantable pig organs. At a National Academy of Sciences meeting on genome editing last week, Church, who co-founded a company called eGenesis for that purpose, reportedly said that his group has successfully created pig embryos with inactivated PERV sequences—the next step toward raising cloned pigs with retrovirus-free organs. That feat isn’t reported in the Science paper. Church says his group has successfully inactivated PERVs in cells from living pigs, and transferred the nuclei of those cells into pig embryos, but wouldn’t confirm that the PERVs were inactivated in the embryos. “We are not ready to discuss the embryo experiment beyond saying that we have done them,” he says.If PERV risks can be taken off the table, cross-species transplantation researchers will have “one less issue to deal with,” says Daniel Salomon, a transplant immunologist and physician at Scripps Research Institute in San Diego, California. But to make transplant-ready pigs, researchers also have to identify the many other molecules in pig cells that cause the human immune system to reject them, and knock the gene for each out in a way that doesn’t kill the pig. Church says his team has such a list, and is working on disabling each of them with CRISPR and other methods. They hope to have immune-friendly, PERV-free embryos ready to implant in surrogate mother pigs in 2016.Church’s success isn’t necessarily good news, says one veteran xenotransplantation researcher. David Cooper, a transplant immunologist whose group at the University of Pittsburgh Medical Center in Pennsylvania is also exploring pig organ transplants, notes that regulatory agencies such as the U.S. Food and Drug Administration (FDA) have already indicated that the presence of PERVs wouldn’t necessarily hold up a clinical trial. In fact, he worries that the newfound ability to remove PERV elements could slow progress in the field as regulators “may now request we do this (without any evidence that it is necessary).”Salomon, who headed an FDA advisory panel on the risks of cross-species transplants, disagrees. “I’m not freaked out about PERV anymore,” he says, but “if you can reduce by 1000-fold the potential of PERV transmission, you should do it.” He also sees an oncoming resurgence in the field as researchers consider ways to edit away all the other features that cause organ rejection. “This first paper on the PERVs shows that that’s not so crazy.”last_img read more

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