The Special Cell of the Delhi Police arrested Sreesanth and the other two cricketers last night from Mumbai for their alleged role in spot-fixing and Related Items
Thanks to a powerful new gene-editing technique, researchers have made a stride toward engineering safer pig organs for human transplants. In a paper in Science today, they describe using the CRISPR editing method in pig cells to destroy potentially harmful DNA sequences at 62 sites in the animal’s genome. It’s the most extreme example to date of the precise yet widespread genetic changes possible through CRISPR. It’s also raising hopes that the technology can finally render pig organs fit for human bodies—a goal that some of the paper’s authors are already pushing further with a private company.About 122,500 people in the United States alone are waiting for a life-saving organ transplant, and some have argued that a steady supply of pig organs could make up the shortage, because they are similar in size to those of people. But so far, no one has been able to get around the violent immune response that pig cells provoke. And these cells pose another, longer term potential risk: Their DNA is riddled with many copies of a DNA sequence that is the remnant of a virus and can still produce infectious viral particles. This porcine endogenous retrovirus (PERV) has been shown to move from pig to human cells in a dish, and to infect human cells transplanted into mice with weak immune systems.These shadowy PERV sequences are the target of the new CRISPR experiment, from geneticist George Church of Harvard University and colleagues. Church believes the new work could revive the idea of xenotransplantation, as the use of animal organs in people is called. “Basically, this whole field has been in the doldrums for 15 years,” he says. “There’s been kind of a few true believers that had it on life support. 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Church’s team designed guide RNA that targets a gene common to all 62 of the PERV sequences in the DNA of pig kidney cells. In a small subset of these cells, the CRISPR system obliterated every instance of the targeted gene—by far greatest the number of gene changes so far achieved with a single round of CRISPR. And those edited cells showed up to a 1000-fold reduction in their ability to infect human kidney cells with PERV in a lab dish.That cells even survived having their DNA hacked up in 62 places is remarkable, says molecular biologist Jennifer Doudna of the University of California, Berkeley, one of the original developers of CRISPR. The same approach could be useful as a research tool to probe the function of many repetitive sequences nestled in the human genome, some of which appear to be activated during viral infections, she says. “Maybe this will encourage labs to say ‘Hey, let’s make a bolder change in one shot.’” Other groups have managed to modify up to six sites, and up to five different genes, at a time.Church cautions that editing many instances of a single, repetitive gene sequence isn’t the same as targeting many unique genes at once—which will be necessary if CRISPR is to become a treatment for complex genetic diseases, for example. He suspects the experiment worked because it took advantage of an apparently rare phenomenon called gene conversion in which DNA sites already inactivated by CRISPR helped stop other recently cut sites from being correctly repaired by the cell, leading to a snowball effect that resulted in all the PERV copies ending up deactivated for good. “We’re not convinced that what we did is generalizable,” he says. “It doesn’t mean that we can now change 62 different genes easily.”But the result has immediate relevance for developing transplantable pig organs. At a National Academy of Sciences meeting on genome editing last week, Church, who co-founded a company called eGenesis for that purpose, reportedly said that his group has successfully created pig embryos with inactivated PERV sequences—the next step toward raising cloned pigs with retrovirus-free organs. That feat isn’t reported in the Science paper. Church says his group has successfully inactivated PERVs in cells from living pigs, and transferred the nuclei of those cells into pig embryos, but wouldn’t confirm that the PERVs were inactivated in the embryos. “We are not ready to discuss the embryo experiment beyond saying that we have done them,” he says.If PERV risks can be taken off the table, cross-species transplantation researchers will have “one less issue to deal with,” says Daniel Salomon, a transplant immunologist and physician at Scripps Research Institute in San Diego, California. But to make transplant-ready pigs, researchers also have to identify the many other molecules in pig cells that cause the human immune system to reject them, and knock the gene for each out in a way that doesn’t kill the pig. Church says his team has such a list, and is working on disabling each of them with CRISPR and other methods. They hope to have immune-friendly, PERV-free embryos ready to implant in surrogate mother pigs in 2016.Church’s success isn’t necessarily good news, says one veteran xenotransplantation researcher. David Cooper, a transplant immunologist whose group at the University of Pittsburgh Medical Center in Pennsylvania is also exploring pig organ transplants, notes that regulatory agencies such as the U.S. Food and Drug Administration (FDA) have already indicated that the presence of PERVs wouldn’t necessarily hold up a clinical trial. In fact, he worries that the newfound ability to remove PERV elements could slow progress in the field as regulators “may now request we do this (without any evidence that it is necessary).”Salomon, who headed an FDA advisory panel on the risks of cross-species transplants, disagrees. “I’m not freaked out about PERV anymore,” he says, but “if you can reduce by 1000-fold the potential of PERV transmission, you should do it.” He also sees an oncoming resurgence in the field as researchers consider ways to edit away all the other features that cause organ rejection. “This first paper on the PERVs shows that that’s not so crazy.”
Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://subscribe.premiersports.tv/ Former Inter owner Massimo Moratti claims “maybe I’d have done something so crazy” and brought back Zlatan Ibrahimovic. Ibrahimovic will become a free agent when his contract with LA Galaxy expires in December, and Il Giornale reported earlier that his agent Mino Raiola had spoken to Inter about a sensational return three weeks ago. The Nerazzurri are currently short in attack after losing Alexis Sanchez to a three-month injury layoff. “Maybe I’d have done something so crazy,” Moratti told Sport Mediaset. “Having said that, there’s a balance that needs maintaining and the players already there have to be respected. “In these cases, all these situations have to be considered.” The 74-year-old then commented on Antonio Conte’s bright start to life with the Beneamata. “His way of being and working hasn’t surprised me. It was already known that he’s full-on and serious as a Coach. “He’s only thinking about Inter and he’s working very well. I think Inter will take their fight down to the wire this season. “Of course, Juventus have shown that they have a better chance, plus they’ve won the last eight Scudetto so they have a different kind of spirit. “However, Inter are also showing that they have both the quality and character needed to fight for the title.”
Referee says ‘air punch, vulgar language’ led to LeBron’s first career ejection LATEST STORIES Memphis Grizzlies center Marc Gasol, front, of Spain, argues for a call as forward Dillon Brooks looks on against the Denver Nuggets in the first half of an NBA basketball game Friday, Nov. 24, 2017, in Denver. (AP Photo/David Zalubowski)Memphis Grizzlies star Marc Gasol said Tuesday he had nothing to do with the struggling NBA team’s decision to sack coach David Fizdale.Fizdale was let go on Monday, a day after a furious Gasol was benched for the fourth quarter of the team’s eighth straight defeat.ADVERTISEMENT Hotel says PH coach apologized for ‘kikiam for breakfast’ claim Memphis started the season 7-4 before the string of losses began. The Grizzlies haven’t won since losing point guard Mike Conley to an Achilles tendon injury seven games ago.Gasol, who is averaging 19.1 points and 9.1 rebounds, admitted he and Fizdale “didn’t see eye to eye all of the time”.“But we both had the same intentions of making the team a collective thing,” he said. “We couldn’t find the formula to do that.”J.B. Bickerstaff was named interim coach and Wallace said he will keep the position for the rest of the season.Bickerstaff went 37-34 as interim coach of the Houston Rockets in 2015-16 after Kevin McHale was fired nine games into the campaign.ADVERTISEMENT MRT 7 on track for partial opening in 2021 Sports Related Videospowered by AdSparcRead Next The Fatted Calf and Ayutthaya: New restos worth the drive to Tagaytay Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ View comments Jordan delivers on promise: 2 Cobra choppers now in PH Malditas save PH from shutout MOST READ Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games But the Spanish big man said he was surprised by the timing of the move.“Nobody likes to see a coach change during the season because you don’t have enough time to work on stuff,” Gasol told reporters on Tuesday. “I was a little bit shocked by it.”FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingMemphis general manager Chris Wallace said the firing of the second-year coach was due to the team being underachievers and not related to any rift between Fizdale and Gasol.“There were bigger trends than just the relationship between the two of them,” Wallace said. “It just hasn’t been going well for us after a good start. And there was no indication that it was going to change magically any time soon.” ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims Don’t miss out on the latest news and information. After 30 years, Johnlu Koa still doing ‘hard-to-make’ quality breads
LATEST STORIES “Some people believe I’m sour or bitter and wanted Rigo to lose, on the contrary, I wanted Walters and Rigo to win because in doing so it gives me the credibility of getting beaten by the top pound-for-pound,” said Donaire.“Staying on the stool with half the fight left, on the other hand, negates the macho image purported by going two weight divisions up.”Sports Related Videospowered by AdSparcRead Next After 30 years, Johnlu Koa still doing ‘hard-to-make’ quality breads Malditas save PH from shutout Depleted Spurs beat Suns for 8th win in 9 games “I fought with bloody hands, I fought with numerous fractures, and sometimes my brain tells me to stop and tells me I’ve done enough but never in my life have I ever quit.”Rigondeux, a natural super bantamweight, moved two weight classes to challenge Lomachenko for the WBO world super featherweight belt and failed after he quit on his stool before the seventh round.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingREAD: Lomachenko stops Rigondeaux in bout between Olympic greats“You could knock me down and I’ll at least attempt to get up,” said Donaire (38-4). “But I won’t quit ever, it is what it is.” Donaire added that he wasn’t bitter losing to Rigendeaux and that he even wanted to see his former opponent to win especially after moving up a couple of weight classes.READ: Donaire yields world boxing title to Rigondeaux“The Filipino Flash” lost to Rigondeaux in 2013 via unanimous decision in their unification bout for the WBA and WBO world super bantamweight titles. Donaire, the current WBC silver featherweight champion even mentioned that he also wanted Nicholas Walters, whom he lost to in 2014, to win against Lomachenko back in 2016.READ: Unbeaten Walters KOs Donaire for titleADVERTISEMENT Don’t miss out on the latest news and information. The Fatted Calf and Ayutthaya: New restos worth the drive to Tagaytay Onyok Velasco see bright future for PH boxing in Olympics PLAY LIST 00:45Onyok Velasco see bright future for PH boxing in Olympics05:25PH boxing team determined to deliver gold medals for PH00:50Trending Articles02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games FILE – Nonito Donaire, left, and Guillermo Rigondeaux face off ahead of their super bantamweight title fight. APA five-division champion, Nonito Donaire knows a thing or two about fighting, so when he saw Guillermo Rigondeux quit mid-fight against Vasyl Lomachenko, that decision did not quite sit well with him.“Incredible performance from Loma, Rigo has never been in this position where he has been dominated every way,” Donaire posted on Twitter Sunday. “But I still can’t understand how a fighter quits.”ADVERTISEMENT ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims MRT 7 on track for partial opening in 2021 Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ MOST READ Jordan delivers on promise: 2 Cobra choppers now in PH Hotel says PH coach apologized for ‘kikiam for breakfast’ claim View comments
Britain’s Andy Murray can focus fully on next week’s Davis Cup assignment in Belgium after Stanislas Wawrinka sent him packing from the ATP World Tour Finals at the O2 Arena on Friday.The concluding round-robin match at the year-ender had become a straight knockout between the two players after Rafael Nadal had already sealed top spot in Ilie Nastase Group, and Wawrinka looked the sharper as he won 7-6(4) 6-4.Also read: Rohan Bopanna-Florin Mergea lose but enter semis Earlier, Nadal spent two hours and 36 minutes beating fellow Spaniard David Ferrer 6-7(2) 6-3 6-4 to make sure he went into Saturday’s semi-final against world number one Novak Djokovic with a 100 percent record so far this week.Wawrinka will face Stan Smith Group winner Roger Federer, who like Nadal was unbeaten in group play.Murray and Wawrinka were both guilty of numerous careless errors, Murray in a first-set tiebreak that he led 4-2.His Swiss opponent then wobbled towards the end and nearly let slip a 5-2 lead, having to save two break points when he served for the match for a second time at 5-4.World number two Murray, who smashed a frame in anger in the final game, said the proximity of next week’s Davis Cup final on a claycourt in Ghent had not been a factor in his defeat.”Way too many errors. Cheap ones, as well. Disappointing,” the 28-year-old, who fell at the group stage for the second year running, told reporters.”I didn’t find it difficult not thinking about the Davis Cup final, to be honest. Obviously the only positive for me this week is I’ve come away from it injury-free.advertisement”Now I have a couple more days to get ready for Belgium.”Murray was straight back on court afterwards, taking out his frustration in a knockup with coach Jonas Bjorkman on a deserted centre court as cleaners picked up litter in the stands.With Nadal already in the semi-finals and Ferrer going home after two defeats, the clash of the Spaniards had no impact on the tournament but the packed arena was treated to the longest match of the tournament so far.It looked as though Nadal might be in for an easy ride when he won 10 of the first 11 points, breaking Ferrer twice, but his 33-year-old opponent is renowned as one of the sport’s best battlers and he hit back to win a tiebreak.World number five Nadal, who had already beaten fourth-ranked Wawrinka and Murray, buckled down though and levelled the match before breaking the Ferrer serve in the final game of the contest.”It should be like this,” Nadal, who has been transformed since a modest summer, told reporters.”Doesn’t matter if I was qualified. For me the main goal is to try to arrive in good shape next year. Today was an opportunity to play against another of the top eight players of the world.”I think I competed well. I won a very tough match. I think a very good match in terms of quality moments.”In the doubles, Ivan Dodig and world number one Marcelo Melo beat Marcin Matkowski and Nenad Zimonjic to set up a semi-final against Rohan Bopanna and Florin Mergea.Second seeds Jean-Julien Rojer and Horia Tecau will face the Bryan twins after beating French duo Pierre-Hugues Herbert and Nicolas Mahut.
Unhappy with the Delhi and District Cricket Association sports committee, Gambhir, Virender Sehwag and a few senior players, had revolted against the administration in 2009. Asked about the revolt, Gambhir said: “Our protest was not for Jaitley ji, it was for other officials of DDCA. We have never taken his name, we have always said that whenever we faced any problems, we had to go to Jaitley ji for everything, which should not have been the case. “If for everything you have to go to Jaitley ji, then whats the role of rest of officials and administrators. Then whats the point of having an association. So, we had problems with other officials then, and even now we have problems with other officials. Me and Sehwag always have had fruitful interactions with Jaitley ji,” he said on the sidelines of an event to support blind Indian cricketers. Asked if he will ever leave Delhi team, Gambhir said: “I have always been a Delhi boy. I have never thought of leaving Delhi. My heart beats for Delhi, I started my career with Delhi and I want to end my cricket with Delhi because I think this is my home team and it has given me the opportunity to play for India. Whatever mess was there or is there, it has given me the opportunity.” The proposed bilateral series between India and Pakistan is still uncertain and Gambhir said it is a decision that the respective governments have to make like always. “Thats a political decision. Always, the decision for India and Pakistan series has gone down to the governments and they have to give the clearance,” Gambhir said. “If you ask any player, they would say, it is always good fun to play against Pakistan. But all the series that has happened in the past has happened with government nod and I am sure whatever decision government will take they will take with the best interest for the country,” he added. Yuvraj Singh and Ashish Nehra made a comeback in Indian squad after they were selected for the T20 series against Australia next month. Asked when can he make a comeback in the India team, Gambhir, who last played for India during a Test against England at The Oval in 2014, said: “It depends on selectors. My job is to play cricket and give my best. “Delhi are in knockouts at Hazare and well look to play well. Every player misses playing for his country but ultimately you have to do what is in your hand,” he said. Asked if India playing the Test series against South Africa in spin-friendly wickets will affect their performance when they tour Australia for ODI and T20 series, Gambhir said: “Its a different format, you cant compare Tests with ODIs.” “When you play ODI cricket, you play on good, even wickets and when you play Test, you prepare wickets for home conditions and that is the case across the world.” PTI ATK PDS PDSadvertisement
Marcos Alonso’s header four minutes from time gave Chelsea the edge over hard-working Slavia Prague with a 1-0 win in the first leg of their Europa League quarter-final in the Czech capital on Thursday. The Spanish left-back capitalised on a fine cross by Brazilian winger Willian, the tireless mastermind of Chelsea’s attack on a chilly night. Willian came close to scoring on 25 minutes but slammed his effort onto the crossbar. “We knew very well that to play here is really very difficult,” Chelsea coach Maurizio Sarri said, pointing out Slavia’s “very physical and aggressive” style. “We had to face difficulties during the match. We were able to face them well and then in the second half we were able to play better. We need to think that the second leg will be difficult because these opponents are very dangerous away. We need to be careful,” Sarri added. Catch up on all the latest sports news and updates here. Also download the new mid-day Android and iOS apps to get latest updates
A new season ahead and a new coach in charge, Sunil Chhetri is an excited man these days. The undisputed leader of Indian football, who will be joining the national camp in Delhi under newly-appointed coach Igor Stimac on Monday, is looking forward to winning more games for India outside the country than on home turf. “I think the next long-term goal should be to qualify for the Asian Cup again,” Chhetri told IANS when asked about what the target of the team should be going into the new season. “That is not going to be easy because lots of things depend on the group you get, the qualifiers, the conditions… you can be unlucky also on several fronts. But that should be our target. “And if you ask the short-term target, then because the boys are ready, we should try to win as many games as possible. We should win more games than we lose. Another target I have is to see we do well when we travel. Generally, we do well at home. Now having given a chance to play the King’s Cup and play friendly games outside the country, we should try to rectify that and win more away games,” he said. Having achieved the target of qualifying for the Asian Cup last time, Chhetri is now confident about India dishing out a better performance in the coming season. “Lots of young players in the team are now matured individuals that gives us hopes. Like Jeje (Lalpekhlua), Sandesh (Jhingan), Udanta (Singh), Gurpreet (Singh Sandhu), Pritam (Kotal), Thapa were youngsters four years back. Now they are all improved and experienced individuals as footballers. “Some of them are still young in age but they know how to play international football. (Anirudh) Thapa, Subhasis (Bose) are not too old but have enough experience. Most of them have cemented their places in the national team. We are a much better team than we were before. With right guidance from the coach, we can surely do than what we did previously in the last five years,” Chhetri said. Jeje, however, is not part of the national camp as he is currently nursing an injury. Asked what should be his expectations from the new coach, Igor Stimac, Chhetri said: “The major thing I want from the coach is to push ourselves. Of course you will want your coach to be tactically sound and knowledgeable and a good man manager. “But the most important thing I want as a player and a captain is that the coach should be demanding. Once you know the coach had a vision and he is good, all the players rally behind him. This coach has a great pedigree. As a player he was amazing. As a coach also he has done decently well. So we all are looking forward to working with him,” he said. “You feel younger when you have a new coach in the camp. It is always challenging to see you have to go and prove again. He will not know who Sunil Chhetri is. For him, everyone is same. That’s a nice thing,” said the scorer of 67 international goals with a laugh. Catch up on all the latest T20 news and updates here. Also download the new mid-day Android and iOS apps to get latest updates
Harry Kane: Tottenham must carry this form into EPL Tottenham Hotspur appoint Jose Mourinho as manager Neuer denied Lucas Moura, but could do nothing to stop Erik Lamela from scoring in the 19th minute courtesy of a perfect pass from Georges-Kevin N’Koudou. Playing with the 1-0 lead, Pochettino revamped the squad to start the second half, introducing Kane, Son and Eriksen. Like Neuer in the first half, Bayern keeper Sven Ulreich handled his first challenge, a shot by Son, but conceded to Eriksen just before the hour mark to put the hosts down 2-0. Two minutes later, however, Jann-Fiete Arp cut the deficit to one, racing down the pitch and putting the ball past Tottenham keeper Paulo Gazzaniga. Ulreich batted away what looked like a sure goal for Kane and Bayern’s Alphonso Davies scored on a great individual effort from outside the area in the 81st minute to level the score at 2-2, where it remained until the final whistle. The penalty shootout extended to 14 rounds, ending only when Gazzaniga stopped Boateng to give Spurs the edge. Catch up on all the latest sports news and updates here. Also download the new mid-day Android and iOS apps to get latest updates Munich: Tottenham Hotspur prevailed over Bayern Munich 6-5 on penalties in the finals to win the Audi Cup. A day after battering Fenerbahce 6-1 in the semi-final, Bayern coach Niko Kovac on Wednesday fielded a starting 11 with only one player older than 24 (goalkeeper Manuel Neuer, 33) — and six age 20 or younger. The 70,000 people in the stands at Munich’s Allianz Arena must have been surprised by the absence of the likes of Robert Lewandowski, Joshua Kimmich, Thiago Alcantara, Jerome Boateng and Thomas Muller. While less radical in his approach, Spurs manager Mauricio Pochettino left Harry Kane, Heung-min Son and Christian Eriksen on the bench at the start of the match.Related News Tottenham Hotspur sack head coach Mauricio Pochettino
I’m what you would call a potential Internet-addict. If left to my devices with nothing special to do, of course, I can check Instagram or Twitter every 15 minutes even though I’m certain there will be nothing new to browse. So when the request to travel to a distant island in the Andaman Islands came up, where there is no TV, phone or Internet connection, it was exciting to step into a new world but it wasn’t what I had in mind.THE NAKED TRUTHThe Andaman and Nicobar Islands, a group of 572 small islands which form an archipelago, are breathtaking – green locks of land floating in the vast Bay of Bengal without a care in the world. Far removed from mainland India and Myanmar, some of them are still inhabited by tribals who continue ancient ways of life, having inhabited it for 60,000 years – the Sentinelese people are among the last in the world to have no contact with the modern world, and the Jarawa tribe came to attention after the 2004 tsunami.PLEASE THE RAIN GODSI boarded an early morning flight for my destination – it was Vistara’s inaugural flight, with a stop-over at Kolkata. At the West Bengal capital, news circulated that heavy rain had hit Port Blair and that we may turn back. Keeping our fingers and toes crossed for half an hour pleased the rain gods it seems, for we were soon on our way.Almost like out of a movie, the lush green islands began to appear in the water as we approached and when we landed in the pleasantly humid weather, we were greeted by a slower pace of life that defines excitement on the somewhat virgin islands.advertisementAn old-school rickety bus took us to the harbour, where a ferry awaited our arrival. The tourist ferry was air conditioned and had two storeys with comfortable seats, a simple lunch and TV screens that introduce you to the history and tourist attractions over the two and a half hour ride.Boats bob at the Havelock harbour.Photo: Mail Today Also Read:9 pictures that capture the beauty of Havelock, Andamans, perfectlyUNDER OPEN SKIESThe first thing that comes to mind when you set foot on Andaman are the scores of freedom fighters who were banished to kala pani or ‘black waters’ for the Cellular Jail in Port Blair after the great sepoy mutiny of 1857. Solitary confinement was the punishment deployed in the building that was constructed with seven outward facing wings, like the spokes of a bicycle wheel, with a tower uniting them in the middle. It is now a National Memorial and the Govind Ballabh Pant Hospital was also set up there to serve the locals.The other islands, however, bear a happier history. Landing at Havelock, we took another rickety but very picturesque bus ride to The Barefoot Eco Hotel. The resort extends into a pristine beach, where there was no one save our motley crew. The loud waves of the ocean rolling in are the only sound you hear, as the water comes to kiss your toes and recede taking the ground from under your feet.The rooms at Barefoot resort are spacious and nestled in a large plantation. Photo: Mail Today BACK TO INNOCENCEThe camera lens can capture only so much, and it’s when you cannot share what you see with others that you begin to share the experience with yourself. You cannot upload them on social media in real time, as the resort has no internet or phone connectivity. After a relaxing walk back to hotel we were served fresh catch of fish, jumbo king size prawns and crab meat with heady cocktails. The luxury of the stay is in the cottages that are made of timber, bamboo and palm leaves. Beautiful thatched roofs and a small balcony lend them a local flavour.The cottages are made of timber, bamboo and palm leaves. Photo: Mail Today SMALL FISH, BIG SEAAt 7:30 am the next morning we headed to Beach no. 7 – Radhanagar to scuba dive. It is surprisingly clean, and littered with small shells that crabs use to make their home – there is a fine of Rs 30,000 for illegally picking up shells as they disturb the natural balance.You need to be completely fit to dive, with no breathing or heart problems, else there is snorkelling. The ocean is a whole new world, like floating in outer space. The corals respond to a click, and schools of silver-blue-green fish swim around you as you furtively enter their home. There are laws of the ocean and as long as you respect them, you will be accepted as part of it. I couldn’t help but be humbled by the expanse of the earth of which I knew so little.advertisementAll kinds of cuisines can be found in the island, especially sea food cooked in Bengali style. Photo: Mail Today Water sports are a must-do in Andaman. Photo: Mail Today PRICE CHECK1. Daily flights from Delhi to Port Blair: Vistara flies via Kolkata, Rs 8,000 onwards2. Ferry from Port Blair to Havelock: Run twice a day, Rs 800 onwards3. The Barefoot Eco Resort: Air-conditioned cottages starting from Rs 9,5004. Things to do: Snorkelling: Rs 3,500 onwards Scuba diving – Rs 3,500 onwards
Share on Twitter Of the many telling facts, stats and scalding-hot takes to emerge from Wednesday night’s Manchester derby – a game that felt as if two clubs were passing briefly on airport travelators, waving curtly as they rolled off in opposite directions – perhaps the most poignant was the touch map of Alexis Sánchez. Facebook Sánchez was on the pitch for only 12 minutes. In that time he touched the ball once. There it is, his single point out there in the middle of all that open space, like a sad, lost penguin wandering the tundra, dreaming of krill.Given the collapse of Sánchez the footballer in the past year it is tempting to apply the old cricket joke about Geoffrey Boycott facing an irresistible Michael Holding at the Kensington Oval. All things considered, Sánchez did well to get one. As peripheral figures go, he has become a compelling subplot in his own right. This is a player signed as a statement of commercial muscle and who remains the most painfully telling aspect in the postmodern drift of Manchester United plc, global retailer of football-flavoured multi-platform product.The direct point of comparison on Wednesday was Bernardo Silva: not an exact match as a footballer, but still a telling one. In many ways the Portuguese is the anti-Sánchez, just as City in their sporting methods are the direct inverse of the belching, leaking, red-shirted juggernaut from across the way. Share on Messenger Reuse this content comment Topics Share on Pinterest Alexis Sánchez Sportblog Share on LinkedIn Every single player in the City team has been improved, some to a startling degree. None of the current squad arrived as a world star. This is a team of Silva not Sánchez, a lesson in having – of all things – a shared idea of how to play, a coherent scheme of recruitment and a sense at its heart of aesthetic enjoyment in its own performance.You could see this in the work rate and indeed the physical courage of the players on Wednesday. City fielded their captain, leader, legend and all-round stumble-prone centre-half, Vincent Kompany. Fernandinho and Ilkay Gündogan both started, the closest Guardiola gets to unleashing his dogs of mild peril. Pinterest Twitter Bernardo Silva was not a headline signing when he arrived in May 2017. By the time City pulled out of the Sánchez rodeo in January last year he had started only six league games. That was also the day City lost 4-3 to Liverpool at Anfield, when he came on as a sub and scored a brilliant late goal.He started the next five games, the pass on Sánchez coinciding with a moment of personal ignition. Those who saw the best of him at Monaco will say this was always likely to happen, that this hyper-intelligent little warrior of the attacking midfield had it in him to eclipse Sánchez completely as a Premier League player within the space of 16 months.As indeed he has now, the divergent courses of these two footballing supertankers embodied by the Sánchez-Silva dynamic. As United shrunk a little at Old Trafford, a disjointed bunch of leftovers and occasional star-turns, City played with an increasing sense of unity, the same steeliness that drove them to a second significant title-chasing win against a top-six team in five days.It is the great paradox of this modern super-club, what you might call the Bernardo principle. From a structural point of view it is tempting simply to marvel at City’s astonishing outlay on players, to feel unease about the use of nation-state funds to distort a sporting league; or to dislike the idea of a venerable old football club being used as a billboard for a dubious Gulf state regime.By contrast, when it comes to sport and the structures of sport enterprise, City are an exemplary presence. Under Guardiola they have become something uplifting on the pitch, a model of fine coaching and shared endeavour. This is not Paris Saint-Germain, not a vehicle for bolt-on superstars, not a story that starts and ends with money buying success. Listen But beyond this they are a titchy team. Early on they were bumped off the ball at times by physically larger opponents. It felt as if it was one of those occasions where the pass-and-move machine might find itself stumbling, works gummed by tension as much as anything else. At half-time City were 45 minutes from seeing the lead in the title race pass back to Liverpool. What turned the game was the shared scurrying efforts of that forward line either side of the interval.Sergio Agüero, despite not scoring, was still out there running like a maniac, the complete team player under this system. Plus, of course, there was that quietly assertive figure on the right of midfield, who would overnight find himself announced as a deserving addition to the PFA team of the year.Burnley away and Leicester City at home present threats of a different kind, but City will still expect to retain the league title. If they do there will be the usual talk of over-spend and soft power projects, all of it worthy of debate on its own terms.Beyond this, sport has a habit of telling its own stories and it is the collectivism in this team, the willingness to improve – what we might call the Bernardo principle – that provides its most salutary lesson. Share on Facebook Share via Email Bernardo Silva celebrates with Sergio Agüero after City’s derby win. Photograph: Simon Stacpoole/Offside/Getty Images He started a little vaguely at Old Trafford. Pushed wide, he completed 21 of his 30 passes in the opening 55 minutes and was bumped around a bit as United tried to assert their advantage in sheer physical size.By the end he had written his name right across the game. There was that beautifully taken opening goal, and after that an increasingly assertive display of hard-running high craft that has become a benchmark for this second-season team.There is one obvious reason – or half a million of them each week – why City didn’t take the chance to sign Mr One-Dot when he was available, the man who might have been in Bernardo Silva’s place had things panned out another way. But this was also a tactical choice.Sánchez’s individualism, not to mention his tendency to lose the ball, would have been a rejection of the basic tone and texture of all Pep Guardiola’s best teams. Plus, of course, City had a different kind of player in mind for that slot, the man from Lisbon who lived in a one-bedroom flat and did his own washing when he played for Monaco, and who has become the most flattering emblem of the Pep end of the City project. Dominant Manchester City show how vast the gulf has become with United Manchester City’s derby delight, focus on Burnley and eggs – Football Weekly Extra Share on WhatsApp Manchester United Manchester City Read more Match of the Day (@BBCMOTD)Alexis Sanchez came on for a total of 12 minutes tonight.This is his touch map…#ManchesterDerby #MUNMCI pic.twitter.com/yHyyaunyQKApril 24, 2019
Live Out Your Westworld Dreams at Casteel Creek Retreat World’s First Luxury Space Hotel Promises Climbing Wall, Low-Gravity Basketball Courts SmithsonianWe’re not breaking new ground by saying that 2001: A Space Odyssey is one of the most iconic movies ever — for lovers of film, art, and space. The Stanley Kubrick and Arthur C. Clarke masterpiece was (is) transcendent, progressive, and decades ahead of its time. Now, thanks to Washington, D.C.’s Smithsonian Museum, we can appreciate the film in a whole new way: by stepping inside it.To honor the landmark film’s 50th anniversary, the Smithsonian’s National Air and Space Museum has unveiled a meticulous, life-sized recreation of “The Barmecide Feast” by Hong Kong-based, British artist Simon Birch. The bedroom scene is among the most recognizable in film history: a beautiful, alien, and sterile melange of Louis XVI-style decor (including Renaissance sculptures and paintings) all set atop a cold, illuminated white floor. Near the end of 2001: A Space Odyssey, cosmonaut Dr. David Bowman awakens unexpectedly in this bizarre bedroom. He proceeds to watch himself transition through various stages of life. Finally, as an old man lying in bed, he sees a black, imposing monolith at the foot of his bed. He reaches for it and suddenly becomes a wide-eyed fetus staring outward from inside a glowing orb of light. It’s largely because of this monolith — and this entire scene — that the film has endured as a subject of discussion for decades. What is the monolith? Where did it come from? Who are we and can we ever hope to move beyond this existential crisis?That anyone was able to painstakingly recreate the set when Kubrick was known for destroying his immediately after filming is nothing short of a miracle. Even the production sketches of the original set designed by NASA-engineer Harry Lange were demolished after production wrapped in 1968. But, as luck would have it, Birch’s own architect, Paul Kember, had surprisingly close ties to the film. Two of Kember’s uncles were draftsman on the original set and had access to the reference materials necessary to recreate it. The only thing missing from the set is the looming black monolith.The bedroom exhibit was previously on temporary display in Los Angeles at Simon Birch’s The 14th Factory in 2017. The Smithsonian reboot is hoping to draw even more attention and is encouraging visitors to photograph and share their visit on social media.Admission to the one-of-a-kind exhibit is free. However, timed tickets must be booked in advance through the official Smithsonian National Air and Space Museum website. Groups of just six visitors will be allowed inside at a time, and only for two minutes. We imagine this will sell out very, very quickly, Dave. This All-Black Cabin is Like a Pair of Binoculars Taking in the Canadian Wilderness Give Your Hypercar the Garage It Deserves with a Custom Aston Martin Lair Editors’ Recommendations Live the High Line Life at This Zaha Hadid-Designed Penthouse
State Minister in the Ministry of Culture, Gender, Entertainment and Sport, Hon. Alando Terrelonge, addresses persons gathered at the National Heroes Park on Sunday (February 10) to reflect on the life of former Jamaican religious revivalist, painter and sculptor, Mallica “Kapo” Reynolds, on the 108th anniversary of his birth, on Sunday (February 10). Kapo was one of the greatest artists in Jamaica’s ‘Intuitives’ artistic movement. He was born in the Byndloss district of St. Catherine and died in 1989 at age 78 years. Also present at the ceremony were members of the creative industry, revivalist movement, diplomats, the Jamaica Cultural Development Commission and other dignitaries. State Minister in the Ministry of Culture, Gender, Entertainment and Sport, Hon. Alando Terrelonge, placing a plant on the tomb of former Jamaican religious revivalist, painter, sculptor and cultural force, Mallica “Kapo” Reynolds, in commemoration of the 108th anniversary of his birth, on Sunday (February 10) at the National Heroes Park in Kingston. Kapo was one of the greatest artists in Jamaica’s ‘Intuitives’ artistic movement. He was born in the Byndloss district of St. Catherine and died in 1989 at age 78 years. Also present at the ceremony were members of the creative industry, revivalist movement, diplomats, the Jamaica Cultural Development Commission and other dignitaries.
gdbiw, March 18, 2014 zoom General Dynamics Bath Iron Works, a business unit of General Dynamics, has been awarded a contract valued at $642.5 million to build another Arleigh Burke-class destroyer for the U.S. Navy.The award brings the total number of ships to be constructed by Bath Iron Works under a multi-year procurement to five, and the total value of the contract to approximately $3.4 billion.There are currently two DDG 51 destroyers in production at Bath Iron Works, Rafael Peralta (DDG 115) and Thomas Hudner (DDG 116). The shipyard began fabrication on DDG 115 in November 2011, and delivery to the Navy is scheduled for 2016. Fabrication on DDG 116 began in November 2012, and that ship is scheduled to be delivered to the Navy in 2017.Bath Iron Works is also building the three ships in the planned three-vessel Zumwalt-class of destroyers, Zumwalt (DDG 1000), Michael Monsoor (DDG 1001) and Lyndon Johnson (DDG 1002). All three ships are progressing in construction with the christening of Zumwalt (DDG 1000) scheduled for April 12, 2014, in Bath, Maine.The Arleigh Burke-class destroyer is a multi-mission combatant that offers defense against a wide range of threats, including ballistic missiles. It operates in support of carrier battle groups, surface action groups, amphibious groups and replenishment groups, providing a complete array of anti-submarine (ASW), antiair (AAW) and anti-surface (SuW) capabilities.Designed for survivability, the ships incorporate all-steel construction and have gas turbine propulsion. The combination of the ships’ AEGIS combat system, the Vertical Launching System, an advanced ASW system, two embarked SH-60 helicopters, advanced antiaircraft missiles and Tomahawk anti-ship and land-attack missiles make the Arleigh Burke class the most powerful surface combatant ever put to sea.
Quotations for key foreign currencies in terms of the Canadian dollar. Quotations are nominal, for information purposes only.Canadian dollar value on Wednesday, the previous day, three-months and one-year: Currency Wed Tue 3 months Year U.S. dollar 1.2505 1.2507 1.3612 1.3189 British Pound 1.6331 1.6319 1.7493 1.7316 Japanese Yen 0.0112 0.0112 0.0122 0.0126 Euro in U.S. 1.1653 1.1667 1.0907 1.0989 Euro in Cdn 1.4572 1.4592 1.4847 1.4493Quotations provided by the Bank of Canada
The Finance Ministry today announced that the price of domestic LP gas will be reduced by Rs. 100 while several other concessions will also take effect from next week.The announcement was made by Finance Minister Ravi Karunanayake today.
Announcing the pilot project on Tuesday, the Fund said it will also help refugees settle down, and begin reintegration process into a community. UN Peacebuilding notes that the project is unique as it reaches across borders and targets the same population, first in asylum in Dadaab, Kenya, and then upon return to Baidoa, Somalia. It builds on an agreement between the governments of Kenya and Somalia and Office of the UN High Commissioner for Refugees (UNHCR) on the voluntary repatriation of Somali refugees living in Dadaab.UNHCR in Kenya, as well as UNHCR, the UN Children’s Fund (UNICEF), the Food and Agriculture Organizations (FAO), the World Food Programme (WFP), the International Organization for Migration (IOM) and the International Labour Organization (ILO) in Somalia will receive the funding. The Peacebuilding Fund is currently also sponsoring other projects in Somalia, aimed at strengthening the national authority in areas liberated from rebel control. The initiative is designed to promote coexistence and peaceful resolution of conflict in Somalia, in addition to supporting the Government’s priorities for stabilization and peace dividends, including investment in jobs. The Fund also aims to continue launching similar initiatives on return and reintegration of refugees.
Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Related21 minibus drivers arrested over traffic offencesJune 27, 2019In “Crime”Bus Driver, Conductor arrested for assaulting Traffic CopFebruary 15, 2019In “Crime”Over 35 minibuses impounded for various traffic offences- PoliceOctober 20, 2018In “Crime” Seventeen persons were arrested for touting while other minibus operators were also detained for various offences.A team of officers attached to the Brickdam Police Station clamped down on the bus parks in Georgetown in a traffic enforcement exercise on Thursday and Friday.Police interacting with the bus operators.Minibus operators were arrested for various offences such as having offensive weapons like knives and ice pickers, tint, breach of road services licence (amplifier set and equalizer in mini-bus), breach of road services licence (offensive words and designs on mini-bus) and defective tire.After the exercise, the ranks took the opportunity to educate the drivers and conductors about the seriousness of these offences and advised them on issues such as seating capacity of a mini-bus, working attire, obstruction of traffic by Stabroek Market area, playing of loud or offensive music, speed limit, cleanliness of the interior of the mini-bus, paying of tickets, insurance of motor vehicles and adhering to all traffic laws and regulations.
It can be baffling how elected legislators — who frequently tout freedom and liberty as core values — often have trouble wrapping their heads around the concept of free speech. Maybe it’s the power that comes from being in office, or the desire to create “heroic” legislation, but politicians often like to propose laws that try to punish those who exercise the rights afforded by the First Amendment. Take William Fourkiller, for example. The Democratic member of the Oklahoma House of Representatives wants to tax the sales of violent video games. He believes that games like Grand Theft Auto desensitize children and encourage childhood obesity and bullying. To combat this problem, he wants to create a 1% tariff on their sales. The tax money would directly benefit state childhood obesity and bullying programs.Fourkiller’s intentions are probably well-meaning. He has a son and, before going into politics, spent 12 years as an elementary school teacher. The proposal could very well be a sincere attempt to look out for young children. That’s something that most of us can relate to.But that reminds me: I just heard a 12-year-old on the street say “F___ the police.” NWA made that phrase famous in their 1988 song of the same name. I don’t think 12-year-olds should be saying such things about the fuzz! Therefore, I propose that we tax the sale of every NWA album and redistribute it to the Chicago Police Sergeant’s Assocation. Heck, while we’re at it, let’s tax every other rap album too, just in case. I believe that this is necessary for the well-being of our country.Of course such a ridiculous proposal would never fly (at least I hope it wouldn’t), because it handcuffs the first amendment and rewards/punishes different types of free speech.Fortunately, Fourkiller’s proposal wouldn’t likely be any more successful in the courts than that one would. Martin Garbus, a NY state First Amendment lawyer, said that it would violate the First Amendment to say that something should get special treatment due to the speech involved. There is some gray area there, relating to a 1968 Supreme Court ruling that allowed states to adopt laws to keep “obscene” material away from children. But that ruling has never been extended to the realm of video games.Politicians are (at least in theory) elected to serve the people. While Fourkiller may earnestly be trying to help the children of Oklahoma, he would also be placing unfair burden on those who simply enjoy blowing stuff up in video games (many of whom are responsible adults). Many vendors (like Gamestop) already prohibit children from buying M for Mature games. Let the parents handle the rest, Mr. Fourkiller, and find other ways to serve your district.via Wired